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Frontline Spot-
On Cat
Contra-indications,
warnings, etc
For animal treatment
only.
Animals should be
weighed accurately prior to treatment.
Do not use in rabbits,
as adverse reactions and even death could occur.
Animals or operators
with a known hypersensitivity to insecticides or alcohol should avoid
contact with FRONTLINE Spot On Cat.
In the absence of
available data, the product should not be used on kittens less than 8
weeks old and/or weighing less than 1kg.
Do not use on sick
(systemic diseases, fever...) or convalescent animals.
Among the extremely
rare suspected adverse reactions, transient cutaneous reactions at the
application site (scaling, local alopecia, pruritis, erythema) and
general pruritis or alopecia have been reported after use.
Exceptionally,
hypersalivation, reversible neurological signs (hyperaesthesia,
depression, nervous signs) or vomiting have been observed after use.
Avoid contact with the
animals eyes.
Fipronil may adversely
affect aquatic organisms. Do not contaminate ponds, waterways or ditches
with the product or empty containers. Dispose of used packaging in the
household refuse.
The product can cause
mucous membrane and eye irritation and so contact with the mouth and
eyes should be avoided.
Avoid contents coming
into contact with the fingers. If this occurs, wash hands with soap and
water. After accidental ocular exposure the eye should be rinsed
carefully with plain water.
Do not smoke, eat or
drink during application.
Treated animals should
not be handled until the application site is dry, and children should
not be allowed to play with treated animals until the application site
is dry. It is therefore recommended that animals are not treated during
the day, but should be treated during the early evening, and that
recently treated animals should not be allowed to sleep with owners,
especially children.
Spot on solution
containing 10% w/v fipronil. Each pipette contains 0.5 ml (50 mg
fipronil).
The treatment
and prevention of infestations by fleas (Ctenocephalides
spp.), ticks (Rhipicephalus spp.,
Dermacentor spp. and
Ixodes spp.) in cats, and as part of a treatment strategy
for Flea Allergy Dermatitis, where this has been previously
diagnosed by a veterinary surgeon. The product controls
infestations with Felicola subrostratus
biting lice on cats. FRONTLINE Spot On Cat can be used in
kittens from 8 weeks of age and weighing at least 1kg.
Dosage
and administration
By topical
application to the skin.
1 pipette
of 0.5 ml per cat (approximately 7.5 - 15 mg/kg).
Hold
upright. Tap the narrow part of the pipette to ensure that
the contents are within the main body of the pipette. Break
back the snap-off top of the spot-on pipette along the
scored line. Part the coat between the shoulder blades until
the skin is visible. Place the tip of the pipette on the
skin and squeeze gently to empty its contents onto the skin,
preferably at two spots, one at the base of the skull and a
second 2-3 cms further back.
Care
should be taken to avoid excessive wetting of the hair with
the product since this will cause a sticky appearance of
hairs at the treatment spot. However, should this occur, it
will disappear within 24 hours post application.
In the
absence of safety studies, the minimum treatment interval is
4 weeks.
It is
important to apply the dose to an area where the animal
cannot lick off and to make sure that animals do not lick
each other after treatment. If licking does occur, a brief
period of hypersalivation may be observed, due mainly to the
nature of the carrier. Ensure that treated animals do not
groom each other after treatment until dry.
Pharmaceutical precautions
Store
in the original package.
Keep
out of reach of children.
Flammable.
Fipronil is a member of the phenylpyrazole family of
non-systemic insecticides/acaricides, which acts by
blocking the GABA receptor to kill the target
parasite on contact.
FRONTLINE Spot On Cat is effective against fleas for
up to 5 weeks in cats and prevents re-infestation
with all stages of Rhipicephalus
spp., Dermacentor spp., and
Ixodes spp. ticks for up to
one month, depending on the level of environmental
challenge. Newly arriving fleas are killed within 24
hours of landing on the animal. Re-treatment may
safely be carried out at one month intervals.
FRONTLINE Spot On Cat is licensed for use as part of
a strategy for the treatment of Flea Allergy
Dermatitis. For this condition, monthly application
to the allergic patient and to other cats in the
household is recommended.
FRONTLINE Spot On Cat does not prevent ticks
attaching to the animal, but ticks will be killed in
the first 24-48 hours after attachment. Once dead,
ticks will often drop off the animal, but any
remaining ticks may easily be removed by a gently
pull, preferably using tweezers. There may be an
attachment of single ticks. For this reason
transmission of infectious diseases cannot be
completed excluded if conditions are unfavourable.
For optimum control of flea problems in a multi-pet
household, all dogs and cats in the household should
be treated with a suitable insecticide. Fleas from
pets often infest the animal's basket, bedding and
regular resting areas such as carpets and soft
furnishings which should be treated, in case of
massive infestation and at the beginning of the
control measures, with a suitable insecticide and
vacuumed regularly.
When treating infestations of lice, all in-contact
cats should be treated with an appropriate product
at the same time.
Laboratory studies using fipronil have not shown any
teratogenic or embryotoxic effect.
The safety of the product was demonstrated in
breeding, pregnant and lactating queens treated with
multiple consecutive doses with up to 3 times the
maximum recommended dose. FRONTLINE Spot On Cat can
be used in breeding, pregnant and lactating queens.
No
adverse effects have been seen in cats and kittens
aged 8 weeks or older and weighing about 1kg treated
monthly with five times the recommended dose for six
consecutive months. However, the risk of adverse
effects may increase with overdosing. Itching may
occur following treatment.
After the topical application of FRONTLINE Spot On
Cat, the products will spread from the site of
treatment to cover the entire surface of the animal
within 24 hours. After application, absorption of
fipronil through the skin is negligible.
No
known incompatibilities exist for the use of other
insecticides or flea control products concurrently
with FRONTLINE Spot On Cat.
There are no data available on the effect of bathing
and shampooing on the efficacy of FRONTLINE Spot On
Cat in cats. However, based on information available
for dogs shampooed from 2 days after application of
the product, it is not recommend to bath animals
within 2 days after application of FRONTLINE Spot On
Cat.
The alcohol carrier may have adverse effects on
painted, varnished or other household surfaces or
furnishings.
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