Equimax Tabs
Contra-indications, warnings, etc
For animal treatment
only.
Do not use in foals
under 2 weeks of age.
Do not use in mares
from which milk is taken for human consumption.
Do not use in horses
known to be hypersensitive to the active ingredients or any of
the other ingredients.
Special warnings for target species:
Care should be taken
to avoid the following practices because they increase the risk
of development of resistance and could ultimately result in
ineffective therapy:
-too frequent and
repeated use of anthelmintics from the same class over an
extended period of time,
-underdosing, which
may be due to underestimation of body weight, misadministration
of the product, or lack of calibration of the dosing device (if
any).
Suspected clinical
cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count
Reduction Test). Where the results of the test(s) strongly
suggest resistance to a particular anthelmintic, an anthelmintic
belonging to another pharmacological class and having a
different mode of action should be used.
Resistance to
ivermectin has been reported in Parascaris
equorum in horses in a number of countries including ones
in the EU. Therefore the use of this product should be based on
national (regional, farm) epidemiological information about
susceptibility of nematodes and recommendations on how to limit
further selection for resistance to anthelmintics.
The product can be
used safely in stallions.
Can be used during
pregnancy and lactation.
Special precautions for use in animals:
Avermectins may not
be well tolerated in all non target species. Cases of
intolerance are reported in dogs, especially Collies, Old
English Sheepdogs and related breeds or crosses, and also in
turtles and tortoises.
Dogs and cats should
not be allowed to ingest spilled tablets or have access to used
packaging due to the potential for adverse effects related to
ivermectin toxicity.
Operator Warnings:
Wash hands after
use. Avoid contact with the eyes. In case of eye irritation,
seek medical attention. Do not eat, drink or smoke while
handling this product. Keep out of the reach of children. In the
event of accidental ingestion, seek medical advice and show the
leaflet to the physician so that he knows what you have taken.
Adverse reactions:
Colic, diarrhoea and
anorexia have been reported in very rare occasions post
treatment, in particular when there is heavy worm burden. In
very rare occasions, allergic reactions such as hypersalivation,
lingual oedema and urticaria, tachycardia, congested mucus
membranes, and subcutaneous oedema have been reported following
treatment with the product.
Withdrawal
Period:
Horses may be
slaughtered for human consumption only after 35 days from the
last treatment.
Container
Disposal:
Any unused
veterinary medicinal product or waste materials derived from
such veterinary medicinal products should be disposed of in
accordance with national requirements. EXTREMELY DANGEROUS TO
FISH AND AQUATIC LIFE. Do not contaminate surface waters or
ditches with the product or used container.
Presentation
White, circular,
biconcave tablet with brown spots.
Each chewable tablet
of 3300 mg contains:
Ivermectin 20mg
Praziquantel 150mg
Uses
For the treatment of
mixed cestode, nematode and arthropod infestations, due to adult
and immature roundworms, lungworms, bots and tapeworms in
horses:
Nematodes
Large-strongyles
Strongylus vulgaris (adult and arterial larvae)
Strongylus edentatus (adult and L4 tissue larval stages)
Strongylus equinus (adult and L4 larval stage)
Triodontophorus spp. (adult)
Small-strongyles
Cyathostomum (adult
and non-encysted mucosal larvae): Cylicocyclus
spp., Cylicostephanus spp.,
Gyalocephalus spp.
Ascarids
Parascaris equorum (adult and larvae).
Pinworms
Oxyuris equi (adult and larvae).
Hairworms
Trichostrongylus axei (adult)
Cestodes ( Tapeworm):
Anoplocephala perfoliata,Anoplocephala
magna, Paranoplocephala mamillana
As tapeworm
infestation is unlikely to occur in horses before two months of
age, treatment of foals below this age is not considered
necessary.
Stomach Bots
Gasterophilus spp. (larvae).
Dosage and
administration
Single oral
administration.
200 µg of ivermectin
and 1.5 mg of praziquantel per kg of bodyweight corresponding to
1 tablet per 100 kg bodyweight.
To ensure a correct
dosage, body weight should be determined as accurately as
possible.
|
Weight
|
Doseage
|
|
up to 100 kg
|
1 tablet
|
|
101 - 200 kg
|
2 tablets
|
|
201 - 300 kg
|
3 tablets
|
|
301 - 400 kg
|
4 tablets
|
|
401 - 500 kg
|
5 tablets
|
|
501 - 600 kg
|
6 tablets
|
|
601 - 700 kg
|
7 tablets
|
|
701 - 800 kg
|
8 tablets
|
Once the correct
dose has been determined, it should be administered in the
following way :
Present the tablet
in the palm of your hand. Repeat this gesture until the complete
dose has been administered. During the initial administration,
the tablet can be combined with a small amount of food or a
treat to increase the acceptance by the horse.
In the event that
the required dose is not ingested an alternative treatment
should be administered. Seek the advice of your veterinary
practitioner.
Advice regarding
appropriate dosing programmes and stock management should be
sought to achieve adequate parasite control for both tapeworm
and roundworm infestations.
Pharmaceutical
precautions
Keep out of reach
and sight of children. Do not store above 30°C
Shelf life of the
veterinary medicinal product as packaged for sale : 18 months
Shelf life after
first opening the immediate packaging : 12 months
Further
information
No known interaction
with other equine medicaments.
A tolerance study
performed in foals with doses up to 5 times the recommended
dosage did not show any adverse reactions.
Safety studies
conducted with a similar veterinary medicinal product (EQUIMAX
oral gel) administered to mares at 3 times the recommended
dosage at 14-day intervals during the whole gestation and
lactation periods did not result in any abortions, nor any
adverse effects during gestation, at parturition or on the mares
general health, nor any abnormalities in the foals.
Safety studies
conducted with a similar veterinary medicinal product (EQUIMAX®
oral gel) administered to stallions at 3 times the recommended
dosage did not show any adverse effects in particular on the
reproductive performances.