Equimax Tabs
Contra-indications,
warnings, etc
For animal treatment
only.
Do not use in foals
under 2 weeks of age.
Do not use in mares
from which milk is taken for human consumption.
Do not use in horses
known to be hypersensitive to the active ingredients or any of the other
ingredients.
Special warnings for target species:
Care should be taken
to avoid the following practices because they increase the risk of
development of resistance and could ultimately result in ineffective
therapy:
-too frequent and
repeated use of anthelmintics from the same class over an extended
period of time,
-underdosing, which
may be due to underestimation of body weight, misadministration of the
product, or lack of calibration of the dosing device (if any).
Suspected clinical
cases of resistance to anthelmintics should be further investigated
using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where
the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class
and having a different mode of action should be used.
Resistance to
ivermectin has been reported in Parascaris equorum
in horses in a number of countries including ones in the EU.
Therefore the use of this product should be based on national (regional,
farm) epidemiological information about susceptibility of nematodes and
recommendations on how to limit further selection for resistance to
anthelmintics.
The product can be
used safely in stallions.
Can be used during
pregnancy and lactation.
Special precautions for use in animals:
Avermectins may not be
well tolerated in all non target species. Cases of intolerance are
reported in dogs, especially Collies, Old English Sheepdogs and related
breeds or crosses, and also in turtles and tortoises.
Dogs and cats should
not be allowed to ingest spilled tablets or have access to used
packaging due to the potential for adverse effects related to ivermectin
toxicity.
Operator Warnings:
Wash hands after use.
Avoid contact with the eyes. In case of eye irritation, seek medical
attention. Do not eat, drink or smoke while handling this product. Keep
out of the reach of children. In the event of accidental ingestion, seek
medical advice and show the leaflet to the physician so that he knows
what you have taken.
Adverse reactions:
Colic, diarrhoea and
anorexia have been reported in very rare occasions post treatment, in
particular when there is heavy worm burden. In very rare occasions,
allergic reactions such as hypersalivation, lingual oedema and urticaria,
tachycardia, congested mucus membranes, and subcutaneous oedema have
been reported following treatment with the product.
Withdrawal Period:
Horses may be
slaughtered for human consumption only after 35 days from the last
treatment.
Container Disposal:
Any unused veterinary
medicinal product or waste materials derived from such veterinary
medicinal products should be disposed of in accordance with national
requirements. EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not
contaminate surface waters or ditches with the product or used
container.
Presentation
White, circular,
biconcave tablet with brown spots.
Each chewable tablet
of 3300 mg contains:
Ivermectin 20mg
Uses
For the treatment of
mixed cestode, nematode and arthropod infestations, due to adult and
immature roundworms, lungworms, bots and tapeworms in horses:
Nematodes
Large-strongyles
Strongylus vulgaris (adult and arterial larvae)
Strongylus edentatus (adult and L4 tissue larval stages)
Strongylus equinus (adult and L4 larval stage)
Triodontophorus spp. (adult)
Small-strongyles
Cyathostomum (adult
and non-encysted mucosal larvae): Cylicocyclus
spp., Cylicostephanus spp.,
Gyalocephalus spp.
Ascarids
Parascaris equorum (adult and larvae).
Pinworms
Oxyuris equi (adult and larvae).
Hairworms
Trichostrongylus axei (adult)
Cestodes ( Tapeworm):
Anoplocephala perfoliata,Anoplocephala magna,
Paranoplocephala mamillana
As tapeworm
infestation is unlikely to occur in horses before two months of age,
treatment of foals below this age is not considered necessary.
Stomach Bots
Gasterophilus spp. (larvae).
Dosage and
administration
Single oral
administration.
200 µg of ivermectin
and 1.5 mg of praziquantel per kg of bodyweight corresponding to 1
tablet per 100 kg bodyweight.
To ensure a correct
dosage, body weight should be determined as accurately as possible.
|
Weight
|
Doseage
|
|
up to 100 kg
|
1 tablet
|
|
101 - 200 kg
|
2 tablets
|
|
201 - 300 kg
|
3 tablets
|
|
301 - 400 kg
|
4 tablets
|
|
401 - 500 kg
|
5 tablets
|
|
501 - 600 kg
|
6 tablets
|
|
601 - 700 kg
|
7 tablets
|
|
701 - 800 kg
|
8 tablets
|
Once the correct dose
has been determined, it should be administered in the following way :
Present the tablet in
the palm of your hand. Repeat this gesture until the complete dose has
been administered. During the initial administration, the tablet can be
combined with a small amount of food or a treat to increase the
acceptance by the horse.
In the event that the
required dose is not ingested an alternative treatment should be
administered. Seek the advice of your veterinary practitioner.
Advice regarding
appropriate dosing programmes and stock management should be sought to
achieve adequate parasite control for both tapeworm and roundworm
infestations.
Pharmaceutical
precautions
Keep out of reach and
sight of children. Do not store above 30°C
Shelf life of the
veterinary medicinal product as packaged for sale : 18 months
Shelf life after first
opening the immediate packaging : 12 months
Further information
No known interaction
with other equine medicaments.
A tolerance study
performed in foals with doses up to 5 times the recommended dosage did
not show any adverse reactions.
Safety studies
conducted with a similar veterinary medicinal product (EQUIMAX oral gel)
administered to mares at 3 times the recommended dosage at 14-day
intervals during the whole gestation and lactation periods did not
result in any abortions, nor any adverse effects during gestation, at
parturition or on the mares general health, nor any abnormalities in the
foals.
Safety studies
conducted with a similar veterinary medicinal product (EQUIMAX® oral
gel) administered to stallions at 3 times the recommended dosage did not
show any adverse effects in particular on the reproductive performances.
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